Researchers at Duke University have come across a small region of the brain, which can be used to reduce pain activity. The region, found in mice, identified over a dozen pain-promoting centers, which provides hopes that new therapies can be developed to target this single population of cells.
The discovery, builds on former research work, where scientists were exploring the impact of general anesthesia on neurons. The study allowed scientists to understand how general anesthesia can block pain neurons in the brain, which can control negative emotions. It als revealed a region of the brain where pain might be pinpointed.
Dr. Paez states "Pain is incredibly complex. Not only does it involve the sensation of pain, it also triggers and creates an emotional response. The research is important as it allows us to identify a specific area of the brain and create treatments to target this area.
Further, Dr. Paez says, "While this study was performed on mice, it is particularly noteworthy. The team used optogentics, this is a treatment where light is used to activate specific cells. When scientists applied this to the mice, the mice stopped displaying symptoms of discomfort and pain such as by paw licking or face wiping.
While further study is required, Dr. Paez believes this study is an important step in determining like areas within the human brain to better target and treat pain.
